VitroINK® Bioinks

Ready-to-use bioinks for 3D bioprinting

VitroINK® are ready-to-use, xeno-free (animal origin-free) bioink system either unmodified or modified with either RGD, Collagen-memetic, IKVAV, or YIGSR peptides or with Matrix Metalloproteinases (MMP) for biodegradable bioink.

VitroINK® is a family of the ready-to-use, xeno-free tunable bioink system that requires no UV,  no temperature/pH curing, or chemical cross-linking. The system is ready-to-use at room temperature, neutral in pH, transparent, and has excellent visibility after printing and cell culture. Due to the unique shear-thinning and rapid recovery mechanical property, VitroINK® can maintain the printed structure without UV or other special curing methods. Adding cell culture medium after printing can further stabilize the printed structure and support cell growth. Cells can be pre-mix with VitroINK® using our VitroINK® Mixing Kit for mixing ratios at 3:1 or 10:1. Different versions of VitroINK® may incorporate multiple biological functional ligands to promote cell attachment, cell-matrix interactions, cell proliferation, motility/migration and differentiation for many different applications.

Specifications

• Xeno-free tunable modified bioink.
• Ready-to-use at room temperature
• No UV, temperature/pH curing, or chemical cross-linking required
• Neutral pH
• Transparent. Excellent visibility after printing and cell culture
• Pre-mix with cells using the included VitroINK® Mixing Kit
• Ships room temperature. Store at 2-8°C
• Size: 3 mL

TheWell products are never to be shipped to residential addresses. This decision has been made to safeguard the improper use and application of these products, particularly in the case of injectables and cell therapy treatments. TheWell has the right to refuse any orders that deem unfit use of their products or violate TheWell’s Terms of Use.   

TheWell products are sold for Laboratory Research Use Only, Not For Diagnostic or Therapeutic use, and are not to be administered to humans.

To ensure a seamless shopping experience, please provide a non-residential shipping address during checkout where your order can be safely received and stored.

For any singular Distributor customer order/sale price of over $5,000 there will be no return allowed. For any order of $0-$4,999 Distributor may cancel/return any or all Products with a 15% restocking fee within 30 days after delivery of products to the customer by Distributor. After 30 days from receipt of the product from the customer, there will be no return allowed.

VitroINK® 10:1 Mixing Component Pack
 
Single-use components for 10:1 mixing ratio for VitroINK® Mixing Kit. DISPENSER NOT INCLUDED

The VitroINK® 10:1 Mixing Component Kit includes a 1 mL syringe, connector and mixing head to replace the one-time-use components in the full VitroINK® Mixing Kit – Complete Pack (Item # IMK00-1) for 10:1 VitroINK® and cells mixing.

This package is sterilized and disposable for one-time use.

Kit Contents and Specifications

• Disposable mixing kit components for VitroINK® kit:
• (1) 1 mL syringe
• (1) connector and tubing
• (1) mixing head
• Sterile
• Use for 10:1 mixing ratio
• Ships room temperature. Store at room temperature.

For any singular Distributor customer order/sale price of over $5,000 there will be no return allowed. For any order of $0-$4,999 Distributor may cancel/return any or all Products with a 15% restocking fee within 30 days after delivery of products to the customer by Distributor. After 30 days from receipt of the product from the customer, there will be no return allowed.

VitroINK® 3:1 Mixing Component Pack

For any singular Distributor customer order/sale price of over $5,000 there will be no return allowed. For any order of $0-$4,999 Distributor may cancel/return any or all Products with a 15% restocking fee within 30 days after delivery of products to the customer by Distributor. After 30 days from receipt of the product from the customer, there will be no return allowed.

VitroINK® Mixing Kit – Complete Pack
 
Mix VitroINK® bioink with cells at 3:1 and 10:1 ratios. Full mixing kit with Dispenser and single-use components.

Mixing cells with the bioink is a critical step for 3D bioprinting. Because of the differences in viscosity of the cell suspension and bioink, the traditional manual mixing methods create a lot of air bubbles and non-uniform mixture which leads to the unstable printed structure, difficulty for cell observation and affect cell viability.

The VitroINK® Mixing Kit was designed to provide a robust mixing of the bioink and cells. Cells can be prepared with VitroINK® for a 3:1 mixing ratio using the 3 mL syringe or a 10:1 mixing ratio using the 1 mL syringe. To prepare the bioprinter cartridge, the VitroINK® and cell suspension are placed in the mixer and is dispensed through the connector and mixing head. Wait 10-20 minutes for the mixture to stabilized and the cartridge is ready for printing. There is no UV, no temperature/pH curing, or chemical cross-linking for the VitroINK® system. Adding cell culture medium to cover the printed structure can further stabilize and support cell growth. The bioprinted cells are ready for incubation.

The syringe, connector and mixing head are disposable for one-time use. Order the sterilized replacement mixing kit components to ensure the robust results for every single mixing.

Kit Contents and Specifications

• Disposable mixing kit components for VitroINK bioink:
• (1) Dispenser
• (1) 1 mL syringe
• (1) 3 mL syringe
• (1) connector and tubing
• (1) mixing head
• Sterile
• Use for 3:1 or 10:1 mixing ratio
• Ships room temperature. Store at room temperature.

For any singular Distributor customer order/sale price of over $5,000 there will be no return allowed. For any order of $0-$4,999 Distributor may cancel/return any or all Products with a 15% restocking fee within 30 days after delivery of products to the customer by Distributor. After 30 days from receipt of the product from the customer, there will be no return allowed.

VitroINK® – Bioink Starter Kits
 
VitroINK® (3 mL) + Full Mixing Kit with Dispenser

VitroINK® Bioink Starter Kit contains both bioink and the complete mixing kit to prepare the cell bioink mixture for 3D bioprinting. The kit includes choice of bioink + the mixing kit:

• VitroINK 3D (3 mL) + VitroINK® Mixing Kit with Dispenser
• VitroINK RGD (3 mL) + VitroINK® Mixing Kit with Dispenser
• VitroINK COL (3 mL) + VitroINK® Mixing Kit with Dispenser
• VitroINK MMP (3 mL) + VitroINK® Mixing Kit with Dispenser
• VitroINK IKVAV (3 mL) + VitroINK® Mixing Kit with Dispenser
• VitroINK YIGSR (3 mL) + VitroINK® Mixing Kit with Dispenser

The VitroINK® Mixing Kit includes a dispenser, 1 mL syringe, 3 mL syringe, connectors and mixing head to get you started.

VitroINK® is a ready-to-use tunable bioink modified with functional ligands, and cell adhesive peptide, promoting cell attachment and cell-matrix interactions. This RGD modified bioink can enhance cell adhesion, proliferation, motility/migration, and differentiation in different applications.

VitroINK® Mixing Kit was designed to provide a robust mixing of bioink and cells. Cells can be prepared with VitroINK® for a 3:1 mixing ratio using the 3 mL syringe or a 10:1 mixing ratio using the 1 mL syringe. Put the VitroINK® and cell suspension in the mixer and gently press the mixture through the connector and mixing head to your bioprinter cartridge. Wait 10-20 minutes for the mixture to stabilize before printing. There is no UV,  no temperature/pH curing, or chemical cross-linking for the VitroINK® system. Simply adding cell culture medium to cover the printed structure can further stabilize and support cell growth. The bioprinted cells are ready for incubation.

Contents and Specifications

VitroINK®

• Xeno-free tunable modified bioink.
• Ready-to-use at room temperature
• No UV, temperature/pH curing, or chemical cross-linking required
• Neutral pH
• Transparent. Excellent visibility after printing and cell culture
• Pre-mix with cells using the included VitroINK® Mixing Kit
• Ships room temperature. Store at 2-8°C
• Size: 3 mL

VitroINK® Mixing Kit

• Complete mixing kit.  Includes:
• (1) 1 mL syringe
• (1) 3 mL syringe
• (1) connector and tubing
• (1) mixing head
• Sterile
• Use for 3:1 or 10:1 mixing ratio
• Size: 3 mL