PR1MA™ Sealing Mats

PR1MA™ 96-Well PCR Sealing Mats are made of silicone, dimensions are 4.67 in. (L) x 2.90 in. (W).

• Pierceable
• Designed for an evaporation-resistant seal to minimize sample loss
• For use in medical, pharmaceutical, food industries, and molecular biology
• Certified free of detectable RNase, DNase, DNA, and PCR inhibitors

OptiWell™ Square Well Sealing Mats

OptiWell™ Square Well Silicone Sealing Mats are designed to provide a secure, leak-proof seal across 24, 96, or 384 well plates, significantly reducing evaporation and sample loss. Ideal for use in PCR, high-throughput screening (HTS), and long-term sample storage, these sealing mats ensure consistent sample integrity and reliable data generation.

Manufactured from high-quality silicone, OptiWell™ Mats offer a tight, uniform seal that fits most standard plate formats, supporting uninterrupted lab workflows and reproducible results. Their durable, reusable design makes them a cost-effective solution for labs seeking efficiency and precision in every experiment.

Key Features

• Leak-proof seal for 24, 96, and 384 well plates
• Minimizes evaporation and sample loss
• Compatible with most major plate brands
• Ideal for PCR, HTS, and sample storage
• Made from durable, high-grade silicone
• Reusable and easy to apply

OptiWell™ Round Well Sealing Mats

Reliable, Leak-Proof Seals for 96 and 384-Well Plates.

OptiWell™ Round Well Sealing Mats are designed to provide a secure, leak-proof seal for 96-well and 384-well round well plates, minimizing evaporation, contamination, and sample loss. Ideal for PCR, high-throughput screening (HTS), and sample storage, these reusable mats ensure consistent sample integrity and reliable data quality.

Manufactured from durable, high-performance materials, OptiWell™ sealing mats create a tight, uniform seal across every well—ensuring uninterrupted workflows and preventing cross-contamination. Their universal fit makes them compatible with most standard round well microplates, including OptiWell™ and other leading brands.

Available in multiple formats to suit various plate configurations, these mats are an essential addition to any high-throughput laboratory setting that demands precision, efficiency, and reproducibility.

Key Features

• Compatible with 96 and 384 round well plates
• Leak-proof seal – prevents evaporation and sample loss
• Ideal for PCR and HTS workflows – protects sample integrity
• Reusable and durable – long-lasting material supports repeated use
• Universally compatible – fits most standard round well plate brands
• Supports high-quality, consistent results – minimizes contamination and variability

ILP PTFE Coated Sealing Mats

ILP PTFE Coated Sealing Mats are engineered from premium medical-grade silicone and coated with PTFE (polytetrafluoroethylene) for unmatched chemical resistance and airtight sealing performance. These high-quality sealing mats are ideal for laboratories requiring secure sample storage, especially in volatile organic compound (VOC) environments or chromatography workflows.

Designed to fit tightly into deep well plates, the mats effectively prevent evaporation, eliminate cross-contamination, and reduce aerosol or pathogen venting. Their self-sealing perforations allow repeated pipette penetration without compromising sample integrity, perfect for automated or manual liquid handling.

These mats are thermally stable and suitable for use across a broad temperature range, making them ideal for incubation, high-temperature storage, or exposure to harsh solvents. Resistant to coring, tearing, and leaching, they ensure no particulate contamination enters your wells.

Fully autoclavable, reusable, and certified RNase-, DNase-, and Pyrogen-free, ILP’s PTFE-coated mats are the preferred choice for chromatography, high-throughput screening, and demanding lab environments.

Key Features

• PTFE-coated for enhanced corrosion and chemical resistance
• Pre-slit options available for easy pipetting and reduced mis-injection
• Perforations self-seal after use, maintaining airtight integrity
• Ideal for chromatography and solvent-sensitive applications
• Free from RNase, DNase, and Pyrogens
• Reusable and autoclavable; no adhesives or extractables

ILP Pre-Slit Sealing Mats

ILP Pre-Slit Sealing Mats are precision-engineered from high-quality compression-molded silicone to provide a secure, airtight seal for deep well plates, microplates, and PCR plates. Designed for demanding lab applications, these mats offer exceptional sealing performance across a wide range of temperatures and chemical conditions, making them ideal for incubation, storage, and solvent-sensitive workflows.

Featuring pre-slit, self-sealing perforations, these mats allow easy pipette access while maintaining a tight seal after each penetration, minimizing evaporation, preventing sample loss, and eliminating cross-contamination. Their chemical-resistant, adhesive-free design ensures sample purity with no extractables, making them suitable for sensitive molecular biology or analytical procedures.

Available scored or pre-cut, with optional PTFE-coated versions for enhanced chemical resistance. All mats include a printed alphanumeric grid for easy well identification and sample tracking.

Key Features

• Pre-slit design for smooth pipetting and reduced injection errors
• Self-sealing perforations maintain airtight integrity after pipette access
• PTFE-coated options available for superior chemical compatibility
• Compatible with deep well, microplates, and PCR plates
• Printed alphanumeric grid for easy well reference
• Chemically resistant, no adhesives or extractables
• Temperature-resistant for high-temp storage and incubation workflows

ILP Sealing Mats - Bulk

Silicone Sealing Mats are engineered for reliable, airtight sealing of deep well plates, microplates, and PCR plates in both automated and manual laboratory workflows. These high-performance mats are ideal for high-throughput screening, sample storage, and protocols requiring frequent plate access.

Made from high-quality, chemically resistant silicone, these mats form a tight seal that helps prevent evaporation of VOCs, minimize sample loss, and eliminate cross-contamination, even during vigorous automation processes. They are thermally stable, making them suitable for incubation and storage in high-temperature environments or use with aggressive solvents.

Each mat includes self-sealing perforations, which maintain an airtight closure after pipette penetration, reducing the risk of aerosol exposure or pathogen venting. Available in scored or pre-slit formats for easy pipetting and reduced mis-injection, with optional PTFE-coated versions offering enhanced resistance to harsh chemicals. A printed alphanumeric grid is included on each mat for easy sample identification.

These mats are sold in bulk quantities, ideal for labs with high usage needs. Choose bulk packs to save time, reduce packaging waste, and ensure uninterrupted workflow.

Key Features

• Designed for bulk laboratory use with deep well, micro, and PCR plates
• Forms an airtight seal to prevent evaporation, contamination, and sample loss
• Perforations self-seal after sample access to maintain integrity
• Available pre-slit for efficient pipetting and workflow speed
• Printed alphanumeric grid for fast sample referencing
• Manufactured with no adhesives or extractables to preserve sample purity
• Temperature-resistant and automation-compatible

Nest Sealing Mats for 96 Well Plates

Nest silicon sealing mats are designed for 96-well storage. Produced from the highest quality research-grade silicone, they are specially designed to provide a positive and airtight seal.

Mats fit tightly into wells preventing evaporation of VOCs, sample loss in storage, cross contamination, and reducing the risk of aerosols and pathogens venting during the automation process. They work in a wide range of temperatures for incubation and storage applications; especially for storage at higher temperatures or for applications involving aggressive solvents.

These seals go well with automation as well as manual laboratory protocols. Often used in high-throughput applications or those involving accessing the sample through the cover multiple times.

High-quality silicone resists coring and tearing, reducing the risk of mat particulate entering the well. Well perforations will seal themselves after penetration, ensuring an airtight closure. These mats are chemically resistant and reusable, containing no adhesives or extractables to contaminate samples.

• High-quality silicone, resists coring and tearing reducing the risk of mat particulate entering the well
• Autoclavable
• May be reused after a 10% bleach wash and ethanol rinse protocol
• Printed alphanumeric grid for easy reference.
• ISO9001&13485 certified
• Manufactured in 100,000 grade cleaning room with USP 6 grade raw materials   

SILICONE SEALING MATS

• Produced from the highest quality research grade silicone, they are specially designed to provide a positive and airtight seal. 
• Mats fit tightly into wells preventing evaporation.
• Pare well with automation as-well-as manual laboratory protocols. 
• High quality silicone, resists coring and tearing reducing the risk or mat particulate entering the well. 
• Well perforations will seal themselves, after penetration, ensuring an airtight closure.
• Made of research-grade silicone, they can be autoclaved, and following a 10% bleach wash and ethanol rinse protocol may be reused.
• Printed alpha numeric grid for easy reference.
• RNase, DNase, DNA, and Pyrogen Free Certification
• Temperature Range: -40C to 80C

This product is no longer available.

For a different Silicone Sealing Mats, visit here.

 

Silicone Sealing Mat for 96 plates

• Made of research-grade silicone
• Scored wells for sample access
• Perforations re-seal after access
• Resists coring and tearing
• Eliminates cross-talk between wells
• Also works as a compression mat
• Suitable for standard PCR thermocycling
• Mats can be reused
• For use with 96-well PCR plates
• Printed alpha numeric grid for easy reference
• Certified to be free of RNase, DNase, DNA, PCR inhibitors, and Pyrogen contamination.

Works as a plate seal (to eliminate cross contamination) and compression mat all-in-one!

Our compression molded 96-round plug, silicone sealing mats for PCR plates minimize sample evaporation in a wide range of temperatures. These mats are chemically resistant and reusable; containing no adhesives or extractables to contaminate samples.  Made of research-grade silicone, they can be autoclaved, and following a 10% bleach wash and ethanol rinse protocol may be reused.

Silicone Sealing Mat for 34, 48, 96, and 384-well