PR1MA™ Nourseothricin Sulfate [NTC] [clonNAT] [Streptothricin Sulfate]

Common Name: [NTC] [clonNAT] [Streptothricin Sulfate]
CAS Number: 96736-11-7
Solubility: Water
Storage Temp: 2-8°C

Dihydrogen sulfate form of the weekly basic antibiotic Nourseothricin consisting of components F, E and D. Effective against gram negative and gram positive bacteria. Also effective against mycobacteria, mycoplasms, protozoa, yeasts, viruses and plants. Commonly used as a selection agent for recombinant yeast strains.

Research or further manufacturing use only, not for food or drug use.

• Appearance: White Powder
• Carbon (C): Report %
• Hydrogen (H): Report %
• Nitrogen (N): Report %
• Purity (HPLC): ≥ 85 %
• Sulfur (S): Report %

PR1MA™  Bacitracin

CAS Number: 1405-87-4
Molecular Weight: 1422.69
Chemical Formula: C₆₆H₁₀₃N₁₇O₁₆ S
Solubility: Water, Ethanol, and Methanol
Storage Temp: 2-8°C

Interferes with bacterial cell wall synthesis. Active against gram positive bacteria. Toxic to plant cells.

Research or further manufacturing use only, not for food or drug use.

• Appearance: White to pale buff powder
• Identification: Pass test
• pH: 5.5 - 7.5
• Loss on Drying: ≤ 5.0 %
• Residue on Ignition: ≤ 0.5 %
• Bacitracin A: ≥ 40.0 %
• SUM of bacitracin A, B1, B2 and B3: ≥ 70.0 %
• Limit of early eluting peptides: ≤ 20.0 %
• Limit of Bacitracin F: ≤ 6.0 %
• Microbial Assay (Dried Basis): ≥ 65.0 IU / mg
• Heavy Metals : ≤ 30 ppm
• Total Viable Aerobic Count: ≤ 100 CFU/g
• Particle Size (< 20 µm by volume): ≥ 99.0 %
• Crystallinity : Pass
• Appearance of Solution: Clear, colorless to slight hazy yellow
• Source: Bacillus Licheniformis
• Non Animal Origin: Non Animal Origin
• Grade: USP
• Country of Origin : Report

PR1MA™ bis-TRIS [bis-(2-hydroxyethyl)aminotris(hydroxymethyl)methane]

Common Name: bis(2-Hydroxyethyl)aminotris (hydroxymethyl)methane
CAS Number: 6976-37-0
Molecular Weight: 209.2
Chemical Formula: C₈H₁₉NO₅
Solubility: Water
Storage Temp: Room Temperature

Research or further manufacturing use only, not for food or drug use.

• Appearance: White crystalline powder
• Assay: ≥ 99.0 %
• Identification (IR): Matches reference
• Melting Point: Report ^oC
• pH, 1.0M Aqueous solution @25ºC: 9.5 - 11.0
• pKa @ 20°C: 6.0 - 7.0
• Solubility: Complete and clear
• UV Absorbance @280nm, 1.0 M in H₂O: ≤ 0.40

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PR1MA™ Citric Acid Anhydrous

CAS Number: 77-92-9
Molecular Weight: 192.1
Chemical Formula: C₆H₈O₇
Solubility: Water
Storage Temp: Room Temperature

Research or further manufacturing use only, not for food or drug use.

• Appearance: Fine white crystalline powder
• Assay (Titration): ≥ 99.5 %
• Carbonizable Substances (H₂SO₄): Pass Test
• Clarity and Color: Pass Test
• Identification: Pass Test
• Lead : ≤ 0.5 mg/kg
• Limit of Oxalic Acid: ≤ 0.036 %
• Oxalate Test: Pass Test
• Residual Solvents: Meet requirements
• Residue on Ignition: ≤ 0.05 %
• Sulfate: ≤ 0.015 %
• Water: ≤ 0.5 %

CAS Number: 1264-72-8
Molecular Weight: 2801.27
Chemical Formula: (C₅₂H₉₈N₁₆O₁₃ )₂ • 5(H₂SO₄)
Solubility: Water
Storage Temp: Short Term: 2-8°C; Long Term: -20°C

Active against gram negative bacteria. Potency approximately 20,000 units per milligram.

Research or further manufacturing use only, not for food or drug use.

• Appearance: White or almost white powder
• Arsenic (As): ≤ 2 ppm
• Heavy Metals : ≤ 20 ppm
• Identification: Conforms
• Loss on Drying: ≤ 3.5 %
• pH (1% in H₂O): 4.0 - 6.0
• Potency (Dried basis): ≥ 19000 µg/mg
• Solubility (50mg/ml in H₂O): Clear and light yellow solution
• Specific Rotation: -73 - -63 °
• Sulfate: 16.0 - 18.0 %
• Sulfated Ash: ≤ 1.0 %

PR1MA™  Polymixin B Sulfate

CAS Number: 1405-20-5
Molecular Weight: 1385.61
Chemical Formula: C₅₅H₉₆N₁₆O₁₃ • 2H₂SO₄
Solubility: Water
Storage Temp: 2-8°C

Mixture of sulfates of polypeptides from certain strains of Bacillus polymixa. Active against gram negative bacteria.

Research or further manufacturing use only, not for food or drug use.

• Appearance: White to Light Yellow Powder
• Identification: Pass Test
• pH (0.5% Solution): 5.0 - 7.5
• Loss on Drying: ≤ 7.0 %
• Single Impurity: ≤ 3.0 %
• Total impurities: ≤ 17.0 %
• Bacteria Colonies: ≤ 10/g
• Ecoli Colonies: Should not be found
• Fungi and Yeast colonies: ≤ 10/g
• Assay, HPLC (on dried basis) (Sum of polymxin B1,B2, B3 and B1-1): ≥ 80.0 %
• Assay, HPLC (on dried basis) (Polymyxin B3): ≤ 6.0 %
• Assay, HPLC (on dried basis) (Polymyxin B1-1): ≤ 15.0 %
• Assay (Dried Basis): ≥ 6000 U/mg
• Assay (Wet Basis): Report U/mg
• Non Animal Origin: Non Animal Origin
• Grade: USP
• Country of Origin: Report

PR1MA™  Spectinomycin Dihydrochloride Pentahydrate

CAS Number: 22189-32-8
Molecular Weight: 495.3
Chemical Formula: C₁₄H₂₄N₂O₇ • 2HCl • 5H₂O
Solubility: Water
Storage Temp: 2-8°C

Aminocyclitol antibiotic that inhibits protein synthesis. Cell culture tested.

Research or further manufacturing use only, not for food or drug use.

• Appearance: White or almost white, Slightly hygroscopic powder
• Identification: Pass Test
• pH @25 °C: 3.8 - 5.6
• Potency : ≥ 603 IU/mg
• Residue after Ignition: ≤ 1.0 %
• Solubility: Clear and colorless to light yellow
• Specific Rotation: +15 - +21 °
• Water (KF): 16.0 - 20.0 %

PR1MA™ Mitomycin C

CAS Number: 50-07-7
Molecular Weight: 334.3
Chemical Formula: C₁₅H₁₈N₄O₅
Solubility: Ethanol
Storage Temp: 2-8°C 

Antineoplastic antibiotic that acts as an alkylating agent after activation and also suppresses the synthesis of nucleic acids. A cell-cylce non specific agent, most active in the late G1 and early S phases.

WARNING! This product can expose you to Mitomycin-C, a chemical which is known to the State of California to cause cancer. For more information go to www.P65Warnings.ca.gov.

Research or further manufacturing use only, not for food or drug use.

• Appearance: Blue violet solid
• Identification (UV): Conforms
• Purity-HPLC (RP CH₃CN:H₂O-0-100%): ≥ 99.0 %
• Purity-HPLC (RP MEOH:H₂O-90-10): ≥ 98.0 %
• Purity-TLC (CH₂CL₂:MEOH- 9:1): ≥ 98.0 %
• Solubility (10 mg/ml MEOH): Clear Blue Solution

PR1MA™  HEPES, Free Acid [N-(2-Hydroxyethyl) piperazine N'-(2-ethanesulfonic acid)]

Common Name: [N-(2-Hydroxyethyl) piperazine N'-(2-ethanesulfonic acid)]
CAS Number: 7365-45-9
Molecular Weight: 238.3
Chemical Formula: C₈H₁₈N₂O₄S
Solubility: Water
Storage Temp: Room Temperature

Zwitterionic N-substituted aminosulfonic acid buffer.

• pka (25°C): 7.5
• pH Range (Working): 6.8 - 8.2
• Heavy Metals: <0.001% Max

• Appearance: White Crystalline Powder
• Assay (Titration, dried basis): ≥ 99.5 %
• DNase, RNase, protease: Not Detected
• Endotoxin (0.2% Solution): ≤ 0.25 EU/ml
• Heavy Metals (as Pb): ≤ 0.001 %
• Identification (IR): Pass
• Iron (Fe): ≤ 0.0005 %
• Loss on Drying: ≤ 1.0 %
• pH (5% in water): 5.0 - 6.5
• pKa @ 20°C: 7.35 - 7.70
• Residue on Ignition: ≤ 0.1 %
• Solubility (1M Solution in Water ): Clear and Colorless Solution
• Sulfate: ≤ 0.05 %
• UV Absorbance (1M@260nm): ≤ 0.05
• UV Absorbance (1M@280nm): ≤ 0.05

PR1MA™ Puromycin Dihydrochloride

CAS Number: 58-58-2
Molecular Weight: 544.43
Chemical Formula: C₂₂H₂₉N₇O₅ • 2HCl
Solubility: Water
Storage Temp: -20°C

Amino nucleoside antibiotic allows the selection of cells expressing the pac gene. Inhibits the growth of gram-positive bacteria and various animal and insect cells.

Research or further manufacturing use only, not for food or drug use.

• Appearance: White to Off White Powder
• Identification (TLC): Conforms
• Melting Point: 168 - 182 ^oC
• Purity (HPLC): ≥ 98.0 %
• Solubility: Clear, colorless or light yellow solution
• Water (KF): ≤ 12.0 %

PR1MA™  Blasticidin S Hydrochloride Powder

CAS Number: 3513-03-9
Molecular Weight: 458.9
Chemical Formula: C₁₇H₂₆N₈O₅ • HCl
Solubility: Water
Storage Temp: -20°C

• Appearance: White Powder
• Endotoxin : ≤ 1.0 EU / mg
• Identification: Pass Test
• Potency: ≥ 850 ug / mg
• Purity (HPLC): ≥ 98.0 %
• Solubility: Clear, Slightly yellow solution at 5 mg / mL in water

PR1MA™  Tris Base Ultra Pure [Tris (Hydroxymethyl) Aminomethane]

Common Name: Tris (Hydroxymethyl) Aminomethane
CAS Number: 77-86-1
Molecular Weight: 121.1
Chemical Formula: C₄H₁₁NO₃
Solubility: Water
Storage Temp: Room Temperature

Highly purified for use in molecular biology applications.

Moisture: <0.2%
Color: <20 APHA (colorless)
Heavy Metals (as Pb): <0.0001%
Insoluble Matter: <0.005%
Heavy Metals: 5 ppm
pKa (20°C): 8.1 ± 0.1

Research or further manufacturing use only, not for food or drug use.

• Appearance: White Crystalline Powder
• Purity (Dried Basis By GC): ≥ 99.9 %
• Related Substances By GC: ≤ 0.1 %
• Water: ≤ 0.2 %
• Loss on Drying @ 105 ^oC, 3hrs: ≤ 1.0 %
• Melting Point: 170 - 172 ^oC
• APHA Color, 20% Aqueous solution: ≤ 20
• Insoluble Matter: ≤ 0.005 %
• Heavy Metals (as Pb): ≤ 5 ppm
• Residue on Ignition: ≤ 0.5 %
• Iron (Fe): ≤ 5 ppm
• UV Absorbance @260nm, 10% Aqueous solution : ≤ 0.03
• UV Absorbance @280nm, 10% Aqueous solution : ≤ 0.02
• UV Absorbance @290nm, 40% solution in H₂O: ≤ 0.20
• UV Absorbance @430nm, 10% Aqueous solution : ≤ 0.004
• Identification A: Pass
• Identification B: Pass
• Identification C: Pass
• pH (5% in water): 10.0 - 11.5
• Arsenic (As): ≤ 1 ppm
• Chloride: ≤ 100 ppm
• Copper (Cu): ≤ 1 ppm
• DNase, RNase, protease: None Detected
• Lead: ≤ 1 ppm
• Magnesium (Mg): ≤ 1 ppm
• pH (1M in H₂O): 10.5 - 11.5
• Residual Solvents: Conforms to USP/EP
• Residue on Ignition (USP): ≤ 0.1 %
• Solubility (2M In H₂O): Pass