TPP TubeSpin® Bioreactors

TPP TubeSpin® Bioreactors have a proven track record in large-scale screening and optimization processes of suspension cells. Designed for efficiency, these tubes allow evaluation of parameters important for production up-scaling while using minimal culture volumes—maximizing the number of parallel experiments possible at the same time.

Suspension cells ranging from immune cells to insect cells, and microorganisms such as E. coli and yeast, can be both cultured and centrifuged directly in TubeSpin® Bioreactors, eliminating the need for transfers before spinning down.

Key Features

• Working volume: 1–35 mL
• Start small suspension cell cultures directly from frozen stocks
• Suitable for bacterial, yeast, and suspension cell cultures (static or shaking)
• Conical bottom for easy pelleting
• 0.22 µm PTFE filter membrane for sterile gas exchange
• Five adjustable openings (A–E) to regulate ventilation as needed
• Fits in standard 15 mL centrifuge rotors
• Dual-purpose: culture and spin in the same tube
• Saves on consumables compared to Erlenmeyer flasks and transfer tubes

Advantages

• Superior gas exchange and defined ventilation control
• Flexible working volumes with one tube type
• Eliminates transfer steps — centrifuge cultures directly
• Enables large-scale, parallel experiments
• Minimizes cell shearing and foam formation (no stirring mechanism)
• Space-saving compared to T-flasks
• Reduces plastic use and waste
• Easy sampling and withdrawal

Applications: Bacterial & Microbiological Cultures

• TPP TubeSpin® Bioreactors are ideally suited for bacteria, yeast, and other microorganisms. Compared to traditional glass test tubes, these disposable tubes save time and effort by eliminating washing and sterilization steps.
• Support aerobic and anaerobic cultures via adjustable filter cap openings
• Culture 1–35 mL volumes per tube — ideal for mini preps, small-scale screens, and downstream workflows
• Disposable format ensures fast setup and reduced contamination risk
• Compatible with CO shaking incubators for parallel high-throughput cultivation

Water Loss Minimization

• When incubating small culture volumes for extended periods, water loss can affect growth. 
• TubeSpin® Bioreactors allow control of evaporation by selectively closing openings above the sterile PTFE filter membrane, while still ensuring effective gas exchange.

Quality Assurance

• Manufactured from high-quality, optically clear plastic
• Sterile, gamma irradiated
• Certified DNase/RNase, nucleic acid, and pyrogen-free

Contact us for free samples and explore how TPP TubeSpin® Bioreactors
can streamline your cell culture workflows.   

Literature and comprehensive information about shaking technology can be found in the "Forum Shaking Technology", a cooperation of TPP with competent partner companies. 
     
  

PR1MA™ 24 Well Half Deep Well Plates

4-Well round polystyrene microplates with transparent bottom and lid (Porvair®).

The PR1MA™ Half Deep Well Plate - 24 is designed for specialized cell cultivation where minimal shear stress is essential. Manufactured from high-quality polystyrene, these microplates feature round wells with a transparent bottom and come with a polystyrene lid, making them ideal for applications such as Growth Profiler analysis and other optical measurements.

Each plate is individually sealed in polyethylene foil, sterilized by gamma irradiation, and non-autoclavable, intended for single-use only. These microplates are a preferred solution for culturing sensitive cells that may not tolerate the angular edges of square-well plates.

With a recommended culture volume of 1 mL (total well volume 3 mL), the PR-CR1424-F performs reliably under standard shaking conditions, 225 rpm with 50 mm orbit or 300 rpm with 25 mm orbit.

For optimal use, pair with Porvair® cover CR1324c and clamp CR1801h for secure sealing and improved cultivation consistency.

Key Features

• 24-well round-bottom microplates made of polystyrene
• Transparent bottom suitable for Growth Profiler and optical measurements
• Gamma-irradiated for sterility
• Single-use; non-autoclavable
• Each plate includes a polystyrene lid and is individually sealed
• Recommended culture volume: 1 mL (well capacity: 3 mL)
• Shaking conditions: 225 rpm / 50 mm orbit or 300 rpm / 25 mm orbit
• Packed in boxes of 16 

Ideal for researchers working with shear-sensitive cell cultures, and in applications where consistent sterility and transparency are critical.

Specifications

Disclaimer

Porvair® is a trademark of Porvair plc. Our products are third-party items designed for compatibility with select Porvair® components. Porvair plc does not manufacture, sponsor, or endorse our products, and is not affiliated with these offerings in any way.
 
 

PR1MA™ 96-Well Half Deep Well Plates

PR1MA™ 96 Half-Deepwell Microplates are high-quality plates designed for high-throughput microbial or cell culture, optimized for use in aerated shaking incubations and growth profiling systems.

Manufactured from pure polystyrene with no additives and sterilized by gamma irradiation, these plates ensure optimal sterility and performance for sensitive cultivation needs.

These half-deepwell plates offer exceptional optical clarity, mixing efficiency, and pellet recovery, making them an ideal choice for biotech, pharmaceutical, and academic laboratories conducting high-throughput screening, growth analysis, and sensitive cultures.

Key Features

• Square wells (8 x 8 mm, 17 mm deep) for space efficiency and consistent mixing
• Recommended working volume of 0.3 mL, with a max of 1.1 mL per well
  Suitable for
  
• Suitable for
• Suitable for 225 rpm (50 mm orbit) or 300 rpm (25 mm orbit) for high oxygen transfer rates
• Ideal for small-volume cultures (up to 1.1 mL per well) 

Available in sterile, single-use boxes of 16, individually wrapped in polyethylene foil for easy handling and contamination prevention.

PR1MA™ Plates for General Cultivation

• General cultivation plates ideal for sensitive microbial or mammalian cell cultures (PR-CR1496-C)
• Compatible with universal clamping systems for secure shaking incubation
• Pyramid bottom design ensures efficient cell pellet collection during centrifugation
• Also available in boxes of 20, 10 plates per sealed bag (PR-CR1496-C10)

PR1MA™ Plates for Growth Profiler Applications

• Standard plate for use in Growth Profiler systems (PR-CR1496-DG)
• Light grey color to minimize optical crosstalk between wells
• Transparent bottom laser-welded, no adhesives used, ensuring optical clarity and assay integrity 

PR1MA™ Plates for Niche Photometric Applications

• 96 Plate designed for specialized photometric assays (PR-CR1496-F)
• Transparent bottom laser-welded, no adhesives used, ensuring optical clarity and assay integrity 

Specifications
 

Item #	Plate Description	Plate Height	Wells	Bottom Style	Vol.	Rec. Culture Vol.	Color
PR-CR1496-C	Square half deepwell	22 mm	96 Wells, 17 mm	V-Bottom	105.6 mL	0.3 mL	Clear
PR-CR1496-C10	Square half deepwell, 20/pk, 10 pks/cs	22 mm	96 Wells, 17 mm	V-Bottom	105.6 mL	0.3 mL	Clear
PR-CR1496-DG	Square half deepwell	22 mm	96 Wells, 17 mm	Transparent	105.6 mL	0.3 mL	Grey/White
PR-CR1496-F	Square half deepwell	22 mm	96 Wells, 17 mm	Transparent	105.6 mL	0.3 mL	Black

 

PR1MA™-Shell Plates - 384-Well, Full Skirted

Discover the next generation of PCR plates: Rugged Polycarbonate Frame + Polypropylene Wells

Engineered for unparalleled durability, PR1MA™-Shell PCR Plates are designed to accommodate all laboratory workflows and are ideal for use on automated liquid handling platforms.

PR1MA™-Shell sets a new standard in performance and convenience.

• The polycarbonate frame is rigid and flat to facilitate a firm grip by robotic arms and ensure reliable placement
• Polypropylene wells provide optimal thermal transfer and higher reaction efficiency
• White well options enhance the fluorescence signal during qPCR
• Wells are slightly raised to ensure evaporation-proof sealing with film, foil, or strip caps
• ANSI/SBS footprint and well spacing
• Vibrant colors offer a visual distinction between different samples or experiments
• Certified free of detectable RNase, DNase, DNA, PCR inhibitors, and tested pyrogen-free 

Proudly made in the USA! Click here for more made in America products!
  

PR1MA™-Shell Plates - 96-Well, Full Skirted

Discover the next generation of PCR plates: Rugged Polycarbonate Frame + Polypropylene Wells

Engineered for unparalleled durability, PR1MA™-Shell PCR Plates are designed to accommodate all laboratory workflows and are ideal for use on automated liquid handling platforms.

PR1MA™-Shell sets a new standard in performance and convenience.

• The polycarbonate frame is rigid and flat to facilitate a firm grip by robotic arms and ensure reliable placement
• Polypropylene wells provide optimal thermal transfer and higher reaction efficiency
• White well options enhance the fluorescence signal during qPCR
• Wells are slightly raised to ensure evaporation-proof sealing with film, foil, or strip caps
• ANSI/SBS footprint and well spacing
• Vibrant colors offer a visual distinction between different samples or experiments
• Certified free of detectable RNase, DNase, DNA, PCR inhibitors, and tested pyrogen-free

Proudly made in the USA! Click here for more made in America products!
 

PR1MA™ Cryo Tubes

• Ultra-pure polypropylene meets FDA 21 CFR 177.1520 & USP Class VI.
• High-contrast black 100 uL graduations are bold and easy to read.
• Large white writing area on all tubes.
• Optimized for vapor-phase liquid nitrogen storage.
• Note: not suitable for immersion in liquid nitrogen.
• Temperature range: -196°C to 121°C.
• HDPE cap has secure lip-seal feature so no O-ring is necessary.
• Maximize tube storage within racks, boxes, and canes.
• Sterile and certified free of detectable DNase, RNase, DNA, PCR inhibitors, and endotoxins.

PR1MA™ 24-Well Deep Well Plates

Manufactured from pure polystyrene with no additives and sterilized by gamma irradiation, these plates ensure optimal sterility and performance. Plates are single-use (non-autoclavable) and come individually wrapped/sealed in polyethylene foil.

• Plates have square wells of 17 x 17 mm and 40 mm deep
• Typical shaking conditions: 225 rpm/50 mm, or 300 rpm/25 mm

Fully Skirted Square 24-Deep Well Microplate with Disposable Cover (PR-CR1424-CDC)

Older version of PR-CR1424-CL. Mainly used with the Thermo Fisher™ Cytomat™ Selector series and for further automation uses.

• Pyramid bottom for easy centrifugation (pellet in center well)
• Comes with a disposable low-evaporation sandwich cover (1.2 mm holes) on top
• Mainly used for automation purposes where the PR-CR1424-CL ridges are an issue 

Square 24-Deep Well Microplates with PS Lid (PR-CR1424-CL)

• Used for leachable-sensitive cultures, such as the cultivation of CHO- and HEK cells
• Pyramid bottom for easy centrifugation (pellet in center well)
• Stackable two high in our universal clamps
• Barcoded version available for sample tracking (PR-CR1424-CLB)

Square 24-Deep Well Microplates with Disposable Cover (PR-CR1424-CLDC)

• Low evaporation disposable covers (1.2 mm holes) mounted on top
• Pyramid bottom for easy centrifugation (pellet in center well)
• Stack three high in our universal clamps 

Grey/White Square 24-Deep Well Microplates with a Transparent Bottom (PR-CR1424-DG)

• Has a transparent bottom and is thus suitable for use in the Growth Profiler
• Light grey to prevent cross-talk between wells, ensuring the most accurate measurements, even at lower ODs 

Extra Tall 4-Position Universal Clamp (PR-CR1812DC-L)

For use with 24-Deep Well Plates and disposable covers.

Special clamping system with ultra-high pillars to support triple-stacked plates and disposable covers, such as the PR-CR1424-CLDC series. Fits various shaker platforms.

If stainless covers are used, only two 24-Deep Well Plates and covers are to be stacked (to prevent a too high center of gravity)

Specifications
 

Item #	Plate Description	Plate Height	Wells	Bottom Style	Vol.	Rec. Culture Vol.	Color
PR-CR1424-CL	Square deepwell w/ disposable PS lid	44 mm	24 Wells, 40 mm	V-Bottom	264 mL	3 mL	Clear
PR-CR1424-CLB	Square deepwell w/ disposable PS lid and barcode	44 mm	24 Wells, 40 mm	V-Bottom	264 mL	3 mL	Clear
PR-CR1424-CDC	Sq. deepwell w/ dispo. sandwich cover, 1.2 mm holes (Cytomat use)	44 mm	24 Wells, 40 mm	V-Bottom	264 mL	3 mL	Clear
PR-CR1424-CLDC	Square deepwell w/ disposable sandwich cover, 1.2 mm holes	44 mm	24 Wells, 40 mm	V-Bottom	264 mL	2.5 mL	Clear
PR-CR1424-DG	Square deepwell, disposable	44 mm	24 Wells, 40 mm	Transparent	264 mL	2.5 mL	Grey/White
PR-CR1812dc-L	Ultra high universal clamp with 4 positions, for triple stacking of 3 MTPs + disposable covers (fits various shaker platforms)

 

Disclaimer

Thermo Fisher™ and Cytomat™ are trademarks of Thermo Fisher Scientific Inc. Our products are third-party items designed for compatibility with Thermo Fisher™ instruments. Thermo Fisher Scientific Inc. does not manufacture, sponsor, or endorse our products, and is not affiliated with these offerings in any way.
 
 

PR1MA™ LTS™ Style Pipette Tips

These tips deliver superior accuracy and precision, ensuring reliable and consistent results. We are proud to manufacture our products in the USA and are committed to sustainability.

Our racks and boxes are made from our exclusive post-consumer resin, while the tips and lids are made from 100% virgin polypropylene for optimum clarity and purity.

These tips are the perfect fit for use with Rainin® LiteTouch® pipettors and are compatible with both single- and multi-channel LiteTouch® pipettors.

• Compatible with Rainin® single- and multi-channel LiteTouch® pipettors
• Light force required to add or eject tips
• Available in racked, sterile, filtered sterile, and reload varieties
• Tips are made from medical-grade virgin polypropylene

• Rack bases and grids are made from our exclusive 50% post-consumer recycled polypropylene—a reduction of up to 30% in the use of virgin polypropylene per rack of tips.

• Proprietary resin technology facilitates clean release
• Certified free of detectable RNase, DNase, DNA, PCR inhibitors, and tested pyrogen-free

Upgrade your pipetting experience with PR1MA™ LTS-Style Tips, which feature ultralow ejection force for comfortable, ergonomic pipetting.

Rainin, LTS and LiteTouch are registered trademarks of Mettler-Toledo Rainin, LLC.

Proudly made in the USA! Click here for more made in America products!

PR1MA™ 2-Well Deep Well Plates

High capacity deep well plates for scalable cell culture and efficient mixing.

Upgrade your cell culture workflow with PR1MA™ 2-Deepwell Microplates, expertly designed to handle larger culture volumes and replace traditional 250 mL flasks. Made from pure polystyrene with no additives, each plate features two deep wells and comes with a transparent polystyrene lid for secure and sterile handling.

Key Features

• Each square well holds approximately 230 mL, ideal for large-scale cultures
• Pyramid bottom design promotes easy and efficient centrifugation, allowing for central pellet formation
• Sterilized by gamma irradiation and non-autoclavable to ensure optimal sterility
• Designed for shaking at 180 rpm (50 mm orbit) or 225 rpm (25 mm orbit) to maximize aeration and mixing efficiency
• Wells are 80 mm deep with slightly rounded corners to reduce foaming during agitation
• Packed in boxes of 4, each plate is individually wrapped in polyethylene foil for easy handling and contamination prevention

• Also available with barcodes (PR-CR1402-LB) for seamless sample tracking   

Perfect for cell culture, bacterial growth, protein expression, or any lab process requiring large volume mixing in a compact format.

Switch to PR1MA™ deep well plates for a more efficient, space-saving alternative to bulky flasks, with better culture control, easier handling, and superior performance.

Specifications
 

Item #	Plate Description	Plate Height	Wells	Bottom Style	Vol.	Rec. Culture Vol.	Color
PR-CR1402-L	Extra high sq. deepwell w/ PS lid	85 mm	2 Wells, 80 mm	V-Bottom	460 mL	60 - 80 mL	Clear
PR-CR1402-LB	Extra high sq. deepwell w/ PS lid & barcode	85 mm	2 Wells, 80 mm	V-Bottom	460 mL	60 - 80 mL	Clear

 

PR1MA™ 6-Well Deep Well Plates

PR1MA™ 6-Deepwell Microplates are high-quality, sterile plates specifically engineered for CHO-cell cultivation. Each plate is constructed from pure polystyrene with no additives, making it ideal for sensitive biological applications. Designed to replace 125 mL shake flasks, these plates offer superior mixing, better scalability, and a smaller lab footprint.

Key Features

• Six Deep Wells Per Plate: Each square well measures 34 x 34 mm, is 80 mm deep, and has a slightly rounded bottom to prevent foaming
• Recommended working volume of 25 to 35 mL per well, with a maximum capacity of 82 mL
• Pyramid-shaped well bottom allows for easy and consistent centrifugation, centralizing cell pellets for simplified downstream processing
• Sterilized by gamma irradiation. Plates are non-autoclavable and individually sealed for contamination control
• Optimized for Shaking Incubators: Suitable for orbital shaking at 180 rpm (50 mm orbit) or 225 rpm (25 mm orbit) to ensure efficient oxygen transfer and mixing.
• Specifically developed for long-term cultivation (4+ days) of Chinese Hamster Ovary (CHO) cells, widely used in biopharma production
• Packed in boxes of 4, each plate is individually wrapped in polyethylene foil for easy handling and contamination prevention 

Available Lid Options

• Standard Polystyrene Lid (PR-CR1406)
• Barcoded Version (PR-CR1406-B) for sample tracking
• Disposable Low-Evaporation Cover (PR-CR1406-DC) 

Low-Evaporation Disposable Cover (PR-CR1406-DC)

Enhance your long-term culture performance with this disposable sandwich-style lid, specifically designed to minimize evaporation during extended incubations.

• Evaporation Control: ~130 uL/well/day at 30°C, 50% humidity
• Air Exchange: 6.5 mL/min per well through 4 mm holes
• Ideal for Extended Cultures: Supports stable growth of CHO cells over 4+ days 

Construction

• Rigid frame from medical-grade polystyrene
• ePTFE membrane filter (0.3 uM) laminated with polyester/polyamide fabric
• PEVA rubber seal (FDA-grade closed-cell foam) for a tight fit and secure seal 

Upgrade to the PR1MA™ 6-Deepwell Plates for more consistent culture performance, improved lab efficiency, and reduced risk of contamination.

Specifications
 

Item #	Plate Description	Plate Height	Wells	Bottom Style	Vol.	Rec. Culture Vol.	Color
PR-CR1406	Extra high square deepwell w/ PS lid	85 mm	6 Wells, 80 mm	V-Bottom	492 mL	25 - 35 mL	Clear
PR-CR1406-B	Extra high square deepwell w/ PS lid and barcode	85 mm	6 Wells, 80 mm	V-Bottom	492 mL	25 - 35 mL	Clear
PR-CR1406-DC	Extra high square deepwell w/ dispo. cover, 4 mm holes	85 mm	6 Wells, 80 mm	V-Bottom	600 mL	25 - 35 mL	Clear

 

FlowTubes™ For Flow Cytometry

FlowTubes™ are high-clarity, 12 x 75 mm polystyrene tubes specifically engineered for use with flow cytometry instruments. Designed for precision and compatibility, each tube features tightly controlled neck dimensions to ensure reliable performance with automated sorting and analysis systems.

Ideal for collecting and preparing dissociated samples,
FlowTubes™ are available in multiple cap configurations to meet your specific needs:

• Standard two-position culture cap
• Cap with integrated 35 uM nylon mesh strainer for simplified sample filtering
• Uncapped option for flexible workflows 

With a 5 mL capacity and made from crystal-clear polystyrene, these tubes offer excellent optical clarity for fluorescence-based applications and ensure smooth operation in automated instruments.

Key Features

• Designed for flow cytometry and cell sorting
• Precision neck dimensions for consistent instrument compatibility
• Available with 35 uM strainer cap, standard cap, or no cap
• Crystal-clear polystyrene for high-clarity fluorescence imaging
• 12 x 75 mm format with 5 mL capacity

Whether you're processing high-throughput cell samples or performing critical FACS analysis, FlowTubes™ deliver the quality and consistency your lab demands.
 

Upright Universal Freezer Racks for 3 in. Boxes

Optimize your freezer space!

• Constructed from durable, corrosion-resistant stainless steel, it is suitable for various freezers, boxes, and samples
• Designed for use with standard cardboard, plastic, or metal boxes
• Cell Dividers protect delicate samples from damage
• Each rack features sturdy handles at both ends to accommodate freezers with right- or left-handed doors

A well-organized lab freezer is crucial for maintaining sample longevity and preserving the freezer compressor.

*Lock device is ordered separately for all 3 in. boxes

Easily identify, retrieve, and protect your life’s work.

Check out our freezer rack configurator to find the perfect freezer rack for you!