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ActionsTheWell Bioscience VitroGel® MMP High Concentration
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VitroGel® MMP High Concentration
Matrix metalloproteinases (MMP) sensitive biodegradable
hydrogel – tunable, xeno-free hydrogel, high concentration (3 mL kit)
- Dilution Solution TYPE 1 contains sucrose for best osmolarity
- Dilution Solution TYPE 2 is a sucrose-free formulation for cells sensitive to the sugar level in the medium
VitroGel® MMP High Concentration is a tunable, xeno-free (animal origin-free) hydrogel system modified with matrix metalloproteinase-sensitive peptides. The enzyme-sensitive hydrogel can be degraded by several MMPs (MMP1, MMP2, MMP3, MMP9, and MMP13) and support different biological activities such as cell proliferation, migration (adhesion/dispersion), differentiation, angiogenesis, apoptosis, etc. VitroGel® MMP High Concentration comes with VitroGel® Dilution Solution to adjust the final hydrogel strength from 10 to 4000 Pa.
VitroGel® High Concentration hydrogels are our xeno-free, tunable hydrogels for researchers wanting full control to manipulate the biophysical and biological properties of the cell culture environment. The tunability of the hydrogel gives the ability to create an optimized environment for cell growth. The hydrogel system has a neutral pH, transparent, permeable, and compatible with different imaging systems. The solution transforms into a hydrogel matrix by simply mixing with the cell culture medium. No cross-linking agent is required. Cells cultured in this system can be easily harvested with our VitroGel® Cell Recovery Solution. The hydrogel can also be tuned to be injectable for in vivo studies.
From 3D cell culture, 2D cell coating to animal injection,
VitroGel® makes it possible to bridge the in vitro and in vivo studies with the
same platform system.
Contents |
VitroGel® MMP
High Concentration, 3 mL |
VitroGel® Dilution
Solution, 50 mL |
|
Hydrogel
Formulation |
Xeno-free
tunable hydrogel modified with matrix metalloproteinases sensitive peptide. |
HIGH
CONCENTRATION |
|
Use |
MMP
sensitive biodegradable hydrogel. |
Mix
& Match |
Can
be blended with other versions of VitroGel to create a multi-functional
hydrogel |
Operation |
Room
temperature |
Hydrogel
Strength |
10 to
4,000 Pa of G’ depending on dilution ratio. |
Dilute
with VitroGel Dilution Solution (TYPE 1 or TYPE 2) for different
concentrations. |
|
pH |
Neutral |
Color |
Transparent |
Cell
Harvesting |
20
min cell recovery using VitroGel® Cell Recovery Solution |
Injectable |
Injectable
hydrogel |
Storage |
Store
at 2-8°C. Ships at ambient temperature |
Number
of Uses |
Dilution
ratio: |
1:2 =
225 uses at 50 µL per well |
|
1:3 =
300 uses at 50 µL per well |
|
1:5 =
450 uses at 50 µL per well |
TheWell products are sold for Laboratory Research Use Only, Not For Diagnostic or Therapeutic use, and are not to be administered to humans.
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