How to Improve DNA & RNA Stability in Buccal Cell and Saliva Samples with Isohelix Products

Saliva and buccal swab sample collection offers a convenient and efficient way to collect DNA and RNA for research and clinical purposes. This non-invasive sample collection method is particularly important as it minimizes discomfort for participants and reduces sample collection costs. DNA and RNA is essential for various applications, including genetic testing, disease diagnostics, and epidemiological studies. Isohelix offers both saliva test kits and buccal swab kits that include sterile buccal swabs.

Sample degradation is often seen in saliva sample collection and can be particularly challenging for RNA buccal swabs. MIDSCI vendor Isohelix provides industry-leading DNA and RNA collection devices with several options for increasing stability, which are available for purchase in the online store.

The Latest Research on Oral Swab Collection Techniques
Isohelix recently shared an article that discusses strategies for simplifying the collection and processing of saliva and buccal swab samples. It highlights the importance of having nucleic acid stabilization options. The article also emphasizes the need for standardized protocols to enhance reproducibility and ease of use, especially for donor self-collection.

Key recommendations include: 

• Selecting the Right Stabilization Option.
  While researching options, consider whether your sample collection will require long-term storage, or if shorter-term storage will suffice. Desiccation and stabilization reagents are two of the stabilization strategies offered by Isohelix.
• Proper Sample Handling Techniques.
  At-home sample collection hinges on ease of use for donors, and the ability to consistently produce contamination-free saliva samples that apply a stabilization strategy. All kits have preprinted instructions that are easy to use and ensure a stabilized sample. Both options of sample integrity in saliva collection and sample integrity in buccal cell collection are available with Isohelix.
• Use Efficient Processing Methods to Streamline Transport Workflows.
  When a cold chain is needed to transport DNA and RNA samples, logistics are more difficult to coordinate — and the cost can be significant. Isohelix offers collection tubes and transport packs that can be sent via standard mail for laboratory processing. Additional options that integrate barcodes and integrate with automation are also available. 

Take a Look at These Isohelix Products:

• Isohelix Genefix DNA Saliva Collection and Stabilization
• Isohelix Genefix Salivalyse Direct to PCR Kit
• Isohelix RNA Isohelix Genefix DNA Saliva Collection and Stabilization
• Isohelix Buccal Swab
• Isohelix Dry Capsules for Swab DNA Stabilization
• Isohelix Buccalfix DNA Stabilization and Lysis Kits
• Isohelix Buccalfix Plus DNA Isolation Kit
• Isohelix RNA Isolation Kit

These products are designed to support best practices for DNA and RNA collection, and stabilization and isolation from buccal cells and saliva, ensuring high-quality results in research and clinical applications. See more swab and saliva collection kits on the MIDSCI online store. 

Get the DNA & RNA Collection Kit Products You Need at MIDSCI
MIDSCI is proud to offer a range of high-quality products from Isohelix to enhance DNA and RNA collection from saliva and buccal swab sample collection. With specialized saliva and buccal cell solutions, Isohelix products are engineered for optimal comfort and efficiency, ensuring reliable sample integrity while minimizing contamination risks. We offer a selection that allows researchers and clinicians to choose the right tools tailored to their specific needs.

With Isohelix products from MIDSCI, professionals can confidently advance their research and/or clinical applications of saliva samples: contributing to more accurate results and better health outcomes. For more information on saliva and buccal swab protocols, or to request a quote, contact MIDSCI online or call us to speak to a product expert: at 1 (800) 227-9997.