Sealing Film

Sealing film plays a vital role in modern molecular biology and life sciences workflows, helping ensure consistent, contamination-free results across PCR, qPCR, cell culture, and high-throughput screening. Whether you’re working with 96-well plates, tissue culture plates, or deep-well blocks, the right microplate sealing film or mat is key to preventing evaporation, ensuring plate sealing integrity, and protecting well contents during incubation, storage, or thermal cycling.

At MIDSCI, we offer high-quality sealing solutions designed for compatibility with standard PCR plates, multi-well plates, and cyclers. Our product range includes adhesive films, pierceable foils, silicone sealing mats, and heat sealing options, all rigorously tested for compatibility.

Types of Sealing Films

Microplate Sealing Films & Tapes

Designed for short-term and long-term storage, these films are available in adhesive, heat-sealing, and pressure-sensitive formats. Options include polypropylene, polyolefin, polystyrene, and polyethylene-based films for a wide range of applications, from PCR and qPCR to ELISA and microscopy.

Microplate Sealing Mats

Silicone sealing mats offer a reusable, autoclavable alternative to disposable films. They provide a secure seal that resists evaporation, leakage, and cross-contamination in assays and incubation processes.

Features and Benefits of Sealing Film

  • Excellent seal integrity across a wide temperature range
  • Adhesive seals that are non-sterile or sterile, depending on the application
  • Compatibility with fluorescence-based assays and microscopy workflows
  • Designed to minimize well-to-well contamination and evaporation
  • Secure seal options for solvents, reagents, and PCR applications
  • Pierceable and resealable designs available for automation or manual pipet access
  • Leak-resistant construction is ideal for short-term storage or long-term storage
  • Heat sealing and foil seal options for enhanced barrier properties
  • Tight seal performance with various PCR plates and well plate types
  • Low autofluorescence options for sensitive detection workflows

Applications of Sealing Film

  • PCR and qPCR: Maintain consistent thermal contact while preventing evaporation and contamination.
  • Cell Culture and Tissue Culture: Seal well plates for incubation without disrupting gas exchange or sample integrity.
  • Assays and High-Throughput Screening: Prevent cross-contamination in fluorescence- or absorbance-based assays.
  • Microscopy and Imaging: Use clear, optically compatible films for accurate, artifact-free imaging.
  • Storage and Transport: Ensure sample integrity in reagents and biological samples during long-term storage.

Compatible Accessories and Related Products

  • Pipettes and pipet tips for accessing sealed wells
  • Cyclers and thermal block instruments for PCR workflows
  • Adhesive applicators and film rollers for even plate sealing
  • Incubators, microplate readers, and high-throughput liquid handlers
  • Reagent reservoirs, plate shakers, and other lab automation tools

Why Choose MIDSCI for Sealing Film

When it comes to plate sealing, MIDSCI brings expert insight and trusted product selection to your lab. Here’s what sets us apart:

  • A full range of sealing film types, from secure seal adhesives to silicone mats and foil seals
  • Compatibility with leading lab brands and plate formats
  • Personalized support to match the best product to your protocol and plate type
  • Fast, reliable shipping with many items in stock and ready to ship
  • A team of real lab experts who understand your challenges in molecular biology, cell culture, and assay design

From optimizing evaporation protection in high-throughput workflows to finding the perfect pressure-sensitive film for a short-term experiment, MIDSCI makes it easier to seal with confidence.

Every application has unique requirements. If you’re unsure whether you need adhesive films, autoclavable mats, or heat sealing options, just reach out. Our lab consultants will help you find the most compatible solution for your workflow, plate type, and equipment.

Disclaimer: Features, applications, and compatibilities described on this page are provided for general reference and may not apply to every product. For detailed information, please review the individual product page or consult with a Lab Consultant to confirm the suitability of a specific product for your application.

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