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PR1MA™ TC9639 Gradient Thermal Cycler

 

The PR1MA™ TC9639 Thermal Cycler provides consistent, reliable results for laboratories with medium to high throughput. From its large, touch-screen user interface to its unique, multi-format block, this cycler is loaded with features. The program wizard and 10 pre-installed programs make it easier than ever to get up and running.

A large, full-color touchscreen serves as the operations center where all functions are accessed. From the “Home” screen, simply touch an icon to view the last run program, enter the program library, or use the program wizard to quickly enter a protocol. In addition, icons for favorite programs can be added for faster access.

The program wizard guides users through quickly setting up a protocol on a single screen. Once entered, programs are shown graphically and can be edited by simply touching the step that requires modification. Time and temperature increments can be built into programs as well as slower ramp rates. Storage capabilities are unlimited; programs can be stored in public folders, private (password-protected) folders, or on a flash drive. The full virtual keyboard allows for alphanumeric naming of programs and folders.

The fully adjustable heated lid prevents condensation and evaporation of samples. Lid temperature can be programmed, and when the block temperature is below 35°C, the lid automatically shuts off. The heating and cooling of the block are precisely and accurately controlled within exceptionally tight tolerances by a proprietary algorithm that simulates sample temperature.

With the multi-format block, there is no need for the expense of multiple interchangeable blocks. The PR1MA™ TC9639 has the flexibility to accept 96 × 0.2 mL tubes, a 96-well plate, 0.2 mL strips or 39 x 0.5 mL tubes all in the same sample block. For protocol optimization, a gradient can be set up across the block. An optional in-situ adapter allows for the incubation of slides. Additionally, the unit may be purchased with a 384-well sample block.

Compatible with PR1MA™ and Accuris™ PCR reagents. For research use only.

 

Features

  • Gradient capabilities- ideal for protocol optimization
  • Intuitive touchscreen control- Works even when wearing gloves!
  • Upgraded software- Even easier to use than before!
  • No need for interchangeable blocks- multi-format accepts:
    • 0.2 mL tubes or strips (96)
    • 0.5 mL tubes (39)
    • 96-well PCR plate

 


Item#:
ASPCRTC2

PR1MA™-Shell Plates - 96-Well, Semi Skirted


Discover the next generation of PCR plates: Rugged Polycarbonate Frame + Polypropylene Wells

 

Engineered for unparalleled durability, PR1MA™-Shell PCR Plates are designed to accommodate all laboratory workflows and are ideal for use on automated liquid handling platforms.

 

PR1MA™-Shell sets a new standard in performance and convenience.

 

·       The polycarbonate frame is rigid and flat to facilitate a firm grip by robotic arms and ensure reliable placement

·       Polypropylene wells provide optimal thermal transfer and higher reaction efficiency

·       White well options enhance the fluorescence signal during qPCR

·       Wells are slightly raised to ensure evaporation-proof sealing with film, foil, or strip caps

·       ANSI/SBS footprint and well spacing

·       Vibrant colors offer a visual distinction between different samples or experiments

·       Certified free of detectable RNase, DNase, DNA, PCR inhibitors, and tested pyrogen-free

 

 

Trust MIDSCI™ for PCR consumables that deliver accurate and reproducible results, empowering you to make groundbreaking discoveries.
Item#:
ASPR1MASHTES96SEMI

PR1MA™ Touch Power Supply

  • Touch screen control
  • Bright color display
  • Dual orientation, auto-rotating display

The PR1MA™ Touch is a workhorse electrophoresis power supply, ideal for the efficient separation of nucleic acids and proteins as well as basic western blotting applications. Four pairs of output jacks are wired in parallel for connecting multiple electrophoresis tanks. A color touch screen allows quick setting and monitoring of all run conditions, including run time, voltage, and current. Users can select “Constant Current” or “Constant Voltage” during an electrophoresis run, keeping the chosen parameter fixed as resistance changes. The dual orientation design with a rotating display allows the PR1MA™ Touch to be installed in the most convenient location, on a shelf or bench, saving valuable space.

 

The PR1MA™ Touch features a logical user interface.

Setting up an electrophoresis run couldn’t be easier; simply touch the parameter to select it, press the “up” and “down” arrows to adjust the value, and then touch “Start”. All parameters are always displayed, with no need to toggle between Time, Voltage, or Amperage. In addition, the run status is always displayed.

 

 

Specifications


Output SettingsConstant voltage or constant current
Voltage Output10 – 300 V (1 V increments)
Current Output4 – 400mA  (1 mA increments)
Max Wattage100 W
Timer1 min. to 20 hours or continuous
Output Terminals4 pairs (wired in parallel)
SafetyNo load detection, overload detection with power limitying function
Display2 x 2 in. color touchscreen
Dimensions8.5 x 6.3 x 4.0 inches
Weight2 lbs
Electrical*100 V to 230 V, 50-60 Hz (Universal Input)
Warranty2 years

 

 

Item#:
ASPR1MAMYVLTTCH

PR1MA™  Non-Skirted PCR Plates

  • PR1MA™ PCR Plates have uniformed wells and ultra-thin walls provide optimal heat transfer and reaction efficiency.
  • Fits most thermal cyclers.
  • High Contrast black alphanumerics for easy well identification.
  • Reclosable bags minimize contamination risk and are convenient for opening and closing.
  • For use in medical, pharmaceutical, food industry, and molecular biology.

Certified free of detectable RNase, DNase, NA, PCR inhibitors, and tested pyrogen-free.

 
PR1MA™ Full-Skirted PCR Plates

 

  • PR1MA™ PCR Plates have uniformed wells and ultra-thin walls provide optimal heat transfer and reaction efficiency.
  • Fits most thermal cyclers.
  • High Contrast black alphanumerics for easy well identification.
  • Reclosable bags minimize contamination risk and are convenient for opening and closing.
  • For use in medical, pharmaceutical, food industry, and molecular biology.
  • Barcoded versions available upon special order. 
  • Certified free of detectable RNase, DNase, NA, PCR inhibitors, and tested pyrogen-free.

 

Mystaire® PCR Prep Stations

They are compact laminar flow enclosures that reduce the risk of sample contamination while performing polymerase chain reaction experiments.


Airborne contaminants are prevented from entering into the work zone through constant positive pressure HEPA filtered air. Each PCR prep station is equipped with a built-in 254 nanometer shortwave lamp to effectively decontaminate the work area between amplifications. Safety interlocks are included on all PCR prep stations to prevent operator exposure to potentially harmful UV radiation.


MY-PCR prep stations are bench-top personal clean zones allowing the operator to amplify RNA and DNA while minimizing the potential for background from airborne contaminants.


Note: MY-PCR and FE-PCR are not biological safety cabinets. They are designed to provide process protection only from potential airborne contaminants found in the laboratory space.


MY-PCR WORKSTATIONS FEATURES

  1. Class 100 vertical laminar flow air
  2. 15-Minute UV light timer
  3. Clear polycarbonate construction with chemically impervious polypropylene work surface
  4. UV shelf with integrated pipette holder
  5. Electrical cord pass-through port

Sash position switch and overlap to prevent UV light exposure

Specs

MY-PCR24

MY-PCR32

MY-PCR48

Width

24"

32"

48"

Depth

24"

Height

30"

Noise Level

<45 DBA

<49 DBA

<56 DBA

Voltage

110 V or 220 V

Power

200 Watts

400 Watts

UV Light

15 W/254 mm

15 W/254 mm (2)

Blower

Sparkless Brushless

UV Light Timer

0-15 min.

Safety Interlock

Yes

Air Velocity

60 LFM

HEPA Filters, Pre-Filters, UV bulbs, additional ports and shelves also available.

Item#:
ACRPCRHOOD4

PR1MA™ Sealing Mats


PR1MA™ 96-Well PCR Sealing Mats are made of silicone, dimensions are 4.67 in. (L) x 2.90 in. (W).

  • Pierceable
  • Designed for an evaporation-resistant seal to minimize sample loss
  • For use in medical, pharmaceutical, food industries, and molecular biology
  • Certified free of detectable RNase, DNase, DNA, and PCR inhibitors
Item#:
ASPR1MAPCRMAT

PR1MA™ Taq

  • Ideal for routine PCR applications as well as genotyping, colony PCR, and fast PCR
  • Improved template affinity and solubility for higher enzyme activity and greater yields
  • Proprietary buffer optimized for a variety of assay conditions
  • Conveniently supplied as a 2X Master Mix or in a 2-tube format of polymerase and separate 5X buffer

 

PR1MA™ Taq provides superior results for routine applications. Modified to improve DNA-binding, this polymerase offers higher solubility and greater template affinity, resulting in consistently superior performance. PR1MA™ Taq Polymerase exhibits a 5' to 3' nuclease activity, but no 3' to 5' (proofreading) activity and works well with a wide range of DNA templates including GC-rich sequences.

 

The polymerase is supplied with a 5X buffer containing MgCl2 and a proprietary mix of enhancers (dNTP's not included). For convenience, PR1MA Taq is also available in a ready-to-use 2X Master Mix - just add primers and template DNA. Our "Red Dye" Master Mix incorporates a red-loading dye that allows amplified samples to be loaded directly on an agarose gel.  The red color aids in visualization during pipetting, and higher density of the buffer ensures that the samples will drop into the gel wells.

 

 


TAKE ADVANTAGE OF THIS SPECIAL PRICING

 on the MultiGene™ OptiMax Gradient Thermal Cycler TC9610 - now $3,088.50  $2,849.00!!

 

Extended Promo!! Now valid 04/01/24 - 06/30/24. Not to be combined with any offers or discounts. No institutional pricing. All terms apply.

 


MultiGene™ OptiMax Thermal Cycler

 

This simple-to-program PCR thermal cycler unit is compact in design and built to perform. Programming is intuitive with the large display and multiple pre-programmed templates supplied with the unit.

 

The OptiMax comes with standard built-in 2-step, temperature optimization, touchdown, and time increment protocols that are easy to adjust to meet your cycling needs. You can select lid temperature or turn it off depending on your needs. The faster ramp rates allow more work to be done in a workday.
 

 

Additional Thermal Cycler Product Features:

  • Unique Flexible Programming with FlexTemp™ technology
  • Fast ramp rates 5°C heating / 3.5°C cooling
  • Simple user interface
  • No condensation after overnight cooling at 4°C
  • 3-Year Warranty

 

Distinct Heat Optimization

The MultiGene™ OptiMax employs a new protocol optimization process improving on older gradient features. This “Better than Gradient” capability allows users to select up to 6 distinct annealing temperatures to be run simultaneously. This is ideal for method optimization as well as applications like genotyping.

 

The OptiMax utilizes FlexTemp™ technology that effectively separates the 96-well plate into 6 – (4 x 4) temperature regions that allow you to pick the temperatures you want to test against. These regions are easily identified by the blue and black squares visible on the microplate platen. Instead of having the thermal cycler choose temperatures for you, you can choose any temperatures you want within a 24°C range.

 

The MultiGene™ OptiMax has a heating rate of 5°C /sec and a cooling rate of 3.5°C/sec. We have minimized overshooting and undershooting so that your reactions only see the temperatures they are supposed to see. This also leads to faster runs time.

 

Intuitive User Interface

The MultiGene™ OptiMax utilizes an intuitive user interface. This user interface is friendly to the laboratory environment and consistent with what our customers previously enjoyed in our earlier models. It can be used with lab gloves even if wet. We have improved the ramping speed and eliminated overshooting and undershooting which contributes to longer run times.

 

Fully Adjustable Heated Lid

The OptiMax’s heated lid is fully adjustable to provide optimum pressure for use with a broad range of tubes and microplates. For optimum performance, the lid can also be programmed to hold different temperatures between 60° to 65°C and 100° to 115°C. The OptiMax lid prevents condensation and slides away and back from the user to provide full access to samples and reduce the risk of coming in contact with a hot surface.


Specifications 

Sample Capacity1 x 96 well plate, 12 8 x 0.2 mL strip tubes,
96 x 0.2 mL tubes
Programmable Temperature Range4°C to 99.9°C
Temperature ControlCalculated or block
Temperature Accuracy/Uniformity±0.5°C/±0.5°C
Heating/cooling methodPeltier
Max. heating/cooling rate4°C/3°C per second
Temperature range of 6-segment blocks30°C to 99°C Temperature of 6-segment blocks
can be set independently.
Maximum Temperature difference between 6-segment blocks24°C
6-segement temperature blocks6 temperature blocks in 4 x 4 well format
Programmable lid temperature60° to 65°C, 100° to 115°C
Program memory200 complete programs
Temp. increments/decrementsYes
User program folders50 sets
Password protected programsYes
CommunicationUSB and RS232 ports
Dimensions (W x D x H)9.4 x 16.5 x 9.8 inches
Weight19.8 lbs
Electrical120 V (TC9610) or
240 V (TC9610-230), 50/60 Hz


 

 

Item#:
ASPCRTC8
  • 96-well, 8 x 12 format
  • Holds 0.2ml PCR tubes, strip tubes, and plates (does not fit full skirted plates)
  • Supplied with clear lift-off lids
Item#:
ASPCRRCKS4

PR1MA™ Untreated Multi-Well Plates

  • Available in 6-, 12-, 24-, 48-, and 96-well format
  • Polystyrene, NOT Tissue Culture Treated (suspension culture)
  • Sterile (gamma irradiated)
  • Plates are labeled with alpha-numeric markings for easy identification of individual wells
  • Each well has a raised rim that nests into the rings on the single-direction lid to reduce evaporation and limit the risk of cross-contamination
  • Lids have a stacking feature for added stability when handling tall stacks of plates 
Item#:
ASCHROPLATES1

PR1MA™ SmartGlow™ DNA Safe Stain

  • Replaces hazardous Ethidium Bromide (EtBr)
  • Better sensitivity than EtBr
  • Detect as little as 0.1ng of DNA
  • Two types available
  • PS Pre Stain
  • LD Loading Dye
  • Excitation by UV light or blue light
  • Compatible with Accuris SmartBlue Transilluminator
  • Ships at ambient temperature (stored at 4°C)


PR1MA™ SmartStain™ PS (Pre-Stain) can be used as a direct replacement for Ethidium Bromide in agarose and polyacrylamide gel electrophoresis. The stain emits green fluorescence when bound to dsDNA or ssDNA and emits red fluorescence when bound to RNA. PR1MA™ SmartStain™ PS exhibits excitation peaks at 290 nm and 490 nm, allowing it to be used with UV and blue light.

Protocol:

  • Prepare 100 mL of agarose or polyacrylamide solution.
  • Add 5 µL of PR1MA™ SmartStain™ to the gel solution before pouring gels.
  • For enhanced results, add PR1MA™ SmartStain™ PS to the running buffer at a ratio of 5 µL per 100 mL. Adding PR1MA™ SmartStain™ PS to the running buffer will result in increased sensitivity and better detection of small quantities of nucleic acid.
  • After electrophoresis is complete, view the gel using a UV or blue light illuminator   
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